Electroactive poly(vinylidene fluoride) electrospun fiber mats coated with polyaniline and polypyrrole for tissue regeneration applications

0548745 - ÚMCH 2023 RIV NL eng J - Journal Article
Hermenegildo, B. - Ribeiro, C. - Peřinka, N. - Martins, P. - Trchová, M. - Hajná, Milena - Stejskal, Jaroslav - Lanceros-Méndez, S.
Electroactive poly(vinylidene fluoride) electrospun fiber mats coated with polyaniline and polypyrrole for tissue regeneration applications.
Reactive and Functional Polymers. Roč. 170, January (2022), č. článku 105118. ISSN 1381-5148. E-ISSN 1873-166X
Institutional support: RVO:61389013
Keywords : tissue engineering * electrospun membranes * poly(vinylidene fluoride)
OECD category: Polymer science
Impact factor: 5.1, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S1381514821003102?via%3Dihub

Electrospun membranes with an active response are playing an increasing role in tissue regeneration by improving the ability of the materials to mimic the cellular microenvironment during cell culture. In this context, this work reports on the development of poly(vinylidene fluoride) (PVDF) electrospun fibers coated with polyaniline (PANI) and with polypyrrole (PPy). Both PANI and PPy successfully coated the fibers, with the surface electrical conductivity of the coatings reaching values of σ = 1.19 S.m−1 for PVDF-PPy and σ = 3.84 × 10−3 S.m−1 for PVDF-PANI. Furthermore, the PVDF samples became hydrophilic upon their coating with either PANI or PPy, the fiber mats adsorbing the water drop after a few seconds. The coated samples remain biocompatible, resulting in a slight improvement in the metabolic activity of L929 fibroblasts.
Permanent Link: http://hdl.handle.net/11104/0325563