Synthetic Biomimetic Polymethacrylates: Promising Platform for the Design of Anti-Cyanobacterial and Anti-Algal Agents

0547601 - BÚ 2022 RIV CH eng J - Journal Article
Mikula, P. - Mlnaříková, M. - Nadres, E. T. - Takahashi, H. - Babica, Pavel - Kuroda, K. - Bláha, L. - Sovadinová, I.
Synthetic Biomimetic Polymethacrylates: Promising Platform for the Design of Anti-Cyanobacterial and Anti-Algal Agents.
Polymers. Roč. 13, č. 7 (2021), č. článku 1025. E-ISSN 2073-4360
Institutional support: RVO:67985939
Keywords : antimicrobials * biometric polymers * cyanobacteria
OECD category: Environmental sciences (social aspects to be 5.7)
Impact factor: 4.967, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/polym13071025

Synthetic biomimetic polymethacrylates (SBPs) were found to be a cost-effective and chemically facile, flexible platform for designing a new type of agent suitable for controlling and mitigating photosynthetic microorganisms. SBPs inhibited the growth of aquatic photosynthetic organisms of concern, i.e., cyanobacteria (Microcystis aeruginosa and Synechococcus elongatus) and green algae (Chlamydomonas reinhardtii and Desmodesmus quadricauda), with 50% effective growth-inhibiting concentrations ranging between 95 nM and 6.5 uM. SBPs also exhibited algicidal effects on C. reinhardtii and cyanocidal effects on picocyanobacterium S. elongatus and microcystin-producing cyanobacterium M. aeruginosa. SBP copolymers, particularly those with moderate hydrophobic content, induced more potent cyanostatic and cyanocidal effects than homopolymers. Thus, biomimetic polymers are a promising platform for the design of anti-cyanobacterial and anti-algal agents for water treatment.
Permanent Link: http://hdl.handle.net/11104/0324457