Scalable production of magnetic fluorescent cellulose microparticles

0545004 - BC 2022 RIV NL eng J - Journal Article
Pospíšková, Kristýna - Mohr, G.J. - Procházková, Jitka - Timko, M. - Rajnák, M. - Paulovičová, K. - Kopčanský, P. - Giovannini, G. - Boesel, L.F. - Šafařík, Ivo
Scalable production of magnetic fluorescent cellulose microparticles.
Cellulose. Roč. 28, č. 12 (2021), s. 7675-7685. ISSN 0969-0239. E-ISSN 1572-882X
R&D Projects: GA MŠMT(CZ) EF17_048/0007399
Institutional support: RVO:60077344
Keywords : cellulose fluorescent particles * magnetic modification * magnetic particles * pH sensors
OECD category: Materials engineering
Impact factor: 6.123, year: 2021
Method of publishing: Limited access
https://link.springer.com/article/10.1007%2Fs10570-021-04018-y

Fluorescent and magnetic nano- and microparticles have already been used for wide range of (bio)applications. Multimodal imaging as well as simultaneous control and monitoring of intracellular movements profit from the combination of these functionalities. Accordingly, several methods have been developed for the synthesis of magnetic fluorescent particles. The majority of these methods, however, require complex modification and purification steps and result in a low yield of particles. Here, we describe a straightforward and scalable method for the magnetic modification of cellulose-based fluorescent particles. The method is based on the use of microwave-synthesized magnetite nanoparticles prepared from ferrous sulfate at high pH. Magnetic modification did not change the pH sensitivity or the optical properties of the fluorescent particles, and allowed them to be manipulated by external magnetic field. Our results demonstrate the possibility of large scale, easy production of bifunctional particles. We anticipate that our method can be expanded to include other types of particles or functionalities relevant for biomedical applications.
Permanent Link: http://hdl.handle.net/11104/0324791