Modular Synthesis of Dendritic Amphiphiles.

0543681 - ÚCHP 2022 CZ eng K - Conference Paper (Czech conference)
Edr, Antonín
Modular Synthesis of Dendritic Amphiphiles.
Proceedings of Abstracts. Prague: Institute of Chemical Process Fundamentals of the CAS, v. v. i., 2021 - (Bendová, M.; Wagner, Z.), s. 14-15. ISBN 978-80-86186-41-2.
[Bažant Postgraduate Conference 2021. Prague (CZ), 23.06.2021-26.06.2021]
Institutional support: RVO:67985858
Keywords : modular synthesis * sythesis * drug carriers
OECD category: Organic chemistry

The synthesis of such structures starts by an attachment of alkyl chain/s R and dendritic wedge/s to the starting molecules. These dendritic wedges are ended by three allyl groups so that various polar groups can be conjugated to the periphery of the wedge by so called thiol-ene click reaction. In addition to the resulting symmetrical structures, a synthesis of their unsymmetrical analogues bearing fluorescent tag on one of its arms (Figure 1) will be presented.
Permanent Link: http://hdl.handle.net/11104/0320861