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Pathogenesis of Retraction Pocket of the Tympanic Membrane-A Narrative Review
- 1.0543676 - ÚŽFG 2022 RIV LT eng J - Journal Article
Urík, M. - Tedla, M. - Hurník, Pavel
Pathogenesis of Retraction Pocket of the Tympanic Membrane-A Narrative Review.
Medicina-Lithuania. Roč. 57, č. 5 (2021), č. článku 425. ISSN 1010-660X. E-ISSN 1648-9144
Institutional support: RVO:67985904
Keywords : retraction pocket * tympanic membrane * pathogenesis
OECD category: Developmental biology
Impact factor: 2.948, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1648-9144/57/5/425
Several theories describe the development of the retraction pocket of the tympanic membrane (RP). Many authors suggest that the negative middle ear pressure is the main reason responsible for developing this condition. A narrative review has been undertaken, and conclusions are drawn reflecting a current knowledge with our new observations in the histological and immunohistochemical study. Recent studies show the important role of inflammation in the development and progression of RP. A review of the available literature shows that the inflammation plays a key role in pathogenesis of the RP and its progression to the cholesteatoma. We support this statement with our new results from histological and immunohistochemical analysis of the RPs.
Permanent Link: http://hdl.handle.net/11104/0320856
Number of the records: 1