A novel Schiff base ligand and its copper complex: Synthesis, characterization, X-ray crystal structure and biological evaluation

0543529 - FZÚ 2022 RIV NL eng J - Journal Article
Kondori, T. - Akbarzadeh-T, N. - Fazli, M. - Mir, B. - Dušek, Michal - Eigner, Václav
A novel Schiff base ligand and its copper complex: Synthesis, characterization, X-ray crystal structure and biological evaluation.
Journal of Molecular Structure. Roč. 1226, Feb (2021), č. článku 129395. ISSN 0022-2860. E-ISSN 1872-8014
R&D Projects: GA MŠMT(CZ) LO1603; GA ČR(CZ) GA18-10504S
EU Projects: European Commission(CZ) CZ.2.16/3.1.00/24510
Institutional support: RVO:68378271
Keywords : Schiff base ligand * X-ray crystallography * antibacterial activity * gram negative * disc diffusion
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 3.841, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.molstruc.2020.129395

A novel Schiff base ligand of (4-nitroaniline-2-hydroxybenzaldehyde) (a) and its complex [Cu(4-nitroaniline-2-hydroxybenzaldehyde)2] (b) were synthesized and characterized by FT-IR, UV–Vis spectroscopy, elemental analysis and X-ray crystallography.The antibacterial activities have been studied invitro against two gram-negative and two gram positive standard bacterial strains. The ligand and its metal chelate were screened for their antimicrobial activities using the disk diffusion method against the selected bacteria. The complex (b) was a stronger antibacterial agent than the free ligand as well as its corresponding metal salt, and it was more active against the gram-positive than gram-negative bacteria.

Permanent Link: http://hdl.handle.net/11104/0320720