Magnetic cobalt oxide nanosheets: green synthesis and in vitro cytotoxicity

0543054 - ÚMCH 2022 RIV US eng J - Journal Article
Raeisi, M. - Alijani, H. Q. - Peydayesh, M. - Khatami, M. - Baravati, F. B. - Borhani, F. - Šlouf, Miroslav - Soltaninezhad, S.
Magnetic cobalt oxide nanosheets: green synthesis and in vitro cytotoxicity.
Bioprocess and Biosystems Engineering. Roč. 44, č. 7 (2021), s. 1423-1432. ISSN 1615-7591. E-ISSN 1615-7605
R&D Projects: GA ČR(CZ) GA17-05007S; GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013
Keywords : green synthesis * cobalt oxide nanoparticles * anticancer effect
OECD category: Physical chemistry
Impact factor: 3.434, year: 2021
Method of publishing: Limited access
https://link.springer.com/article/10.1007%2Fs00449-021-02518-6

Cobalt oxide nanoparticles were prepared via green chemistry route and fully characterized by Field Emission Scanning Electron Microscope (FESEM), Energy-dispersive X-ray spectroscopy (EDAX), X-ray diffraction (XRD), High-resolution transmission electron microscopy (HRTEM) and Transmission electron microscopy (TEM) analyses. The CoO and Co3O4 nanoparticles, in sheet-shaped cobalt oxide form, ensued simultaneously in one step. The varying concentrations of NPs were analyzed via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test on the cancer cell line (U87) which revealed that with increasing concentration of cobalt oxide nanoparticles, the survival rate of U87 tumor cells decreases, IC50 of nanoparticles being ~ 55 µg/ml−1.
Permanent Link: http://hdl.handle.net/11104/0321233