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Effective control of optical purity by chiral HPLC separation for ester-based liquid crystalline materials forming anticlinic smectic phases
- 1.0541667 - FZÚ 2022 RIV GB eng J - Journal Article
Vojtylová-Jurkovičová, Terézia - Vaňkátová, Petra - Urbańska, M. - Hamplová, Věra - Sýkora, D. - Bubnov, Alexej
Effective control of optical purity by chiral HPLC separation for ester-based liquid crystalline materials forming anticlinic smectic phases.
Liquid Crystals. Roč. 48, č. 1 (2021), s. 43-53. ISSN 0267-8292. E-ISSN 1366-5855
R&D Projects: GA MŠMT(CZ) EF16_019/0000760; GA MŠMT(CZ) 8J20PL008; GA ČR GA19-03564S
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760; EU - ICT(XE) COST Action CA17139
Institutional support: RVO:68378271
Keywords : High-performance liquid chromatography * self-assembling behaviour * fluorinated materials * chiral liquid crystals * chiral separation * racemic mixtures
OECD category: Organic chemistry
Impact factor: 2.676, year: 2021
Method of publishing: Limited access
https://doi.org/10.1080/02678292.2020.1762937
Effective control of optical purity by chiral separation of (S) and (R) enantiomers remains an actual and highlighted task while designing new chiral organic materials. An efficient methodology to solve this task has been developed and verified on a specifically designed series of chiral fluorinated liquid-crystalline materials with lateral substitution on the molecular core. HPLC was done using amylose based stationary phases. The self-assembling behaviour of new racemic materials was established. While establishing the chiral separation behaviour, the optimal separation conditions were taken over from our previous study and used for two chiral columns with coated amylose as chiral selector. Interestingly, two racemic materials demonstrated an unexpected change in enantiomer elution order. This is a very important information from separation point of view, e.g. preparative chiral chromatography.
Permanent Link: http://hdl.handle.net/11104/0319199
Number of the records: 1