Nanoparticles in human life: friends or foes?

0540553 - ÚEM 2021 RIV CZ eng M - Monography Chapter
Holáň, Vladimír - Rössner ml., Pavel
The Impact of a Long-term Continuous Inhalation of Nanoparticles on Cells and Functions of the Immune System.
Nanoparticles in human life: friends or foes? Praha 3: Proxima Tisk s.r.o., 2020 - (David, L.), s. 72-78. ISBN 978-80-906655-9-0
R&D Projects: GA MŠMT(CZ) LO1508
Institutional support: RVO:68378041
Keywords : nanoparticles * inhalation * immune system * cell subpopulations * immunological reactivity
OECD category: Genetics and heredity (medical genetics to be 3)

This review article summarizes our results from the studies of effects of nanoparticles on functions of cells of the immune system. We demonstrated that a long-term inhalation of coper oxide or zinc oxide nanoparticles negatively influences the composition of the major leucocyte populations in the spleen and modifies the reactivity of cels of the innate and adaptive immune system. However, the effects of nanoparticles strongly depend on the type of particles and on the duration of inhalation.
Permanent Link: http://hdl.handle.net/11104/0318352