Number of the records: 1
Mitogenomics of the endemic Ethiopian rats: looking for footprints of adaptive evolution in sky islands
- 1.0538392 - ÚBO 2022 RIV NL eng J - Journal Article
Bartáková, Veronika - Bryjová, Anna - Nicolas, V. - Lavrenchenko, L. A. - Bryja, Josef
Mitogenomics of the endemic Ethiopian rats: looking for footprints of adaptive evolution in sky islands.
Mitochondrion. Roč. 57, March (2021), s. 182-191. ISSN 1567-7249. E-ISSN 1872-8278
R&D Projects: GA ČR(CZ) GA18-17398S
Institutional support: RVO:68081766
Keywords : adaptation * NADH dehydrogenase * adaptive introgression * dN/dS * oxidative phosphorylation * positive selection
OECD category: Zoology
Impact factor: 4.534, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S1567724920302464?via%3Dihub
Organisms living in high altitude must adapt to environmental conditions with hypoxia and low temperature, e.g. by changes in the structure and function of proteins associated with oxidative phosphorylation in mitochondria. Here we analysed the signs of adaptive evolution in 27 mitogenomes of endemic Ethiopian rats (Stenocephalemys), where individual species adapted to different elevation. Significant signals of positive selection were detected in 10 of the 13 mitochondrial protein-coding genes, with a majority of functional substitutions in the NADH dehydrogenase complex. Higher frequency of positively selected sites was found in phylogenetic lineages corresponding to Afroalpine specialists.
Permanent Link: http://hdl.handle.net/11104/0316205
Number of the records: 1