Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites

0534555 - ÚOCHB 2021 RIV eng P - Patent Document
Navrátil, Václav - Šácha, Pavel - Schimer, Jiří - Konvalinka, Jan - Majer, Pavel
Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites.
2020. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. Date of the patent acceptance: 21.07.2020. Patent Number: US10718772
R&D Projects: GA MŠMT LO1302; GA MZd(CZ) NV15-31379A
Institutional support: RVO:61388963
Keywords : DIANA * inhibitor * analyt
OECD category: Biochemical research methods
https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20200721&DB=&locale=en_EP&CC=US&NR=10718772B2&KC=B2&ND=4

A method for detection of active form of analytes in a sample and/or for determination of ability of tested substances to bind to the active site of these analytes has the following steps: a) analyte or group of analytes from the sample is immobilized on the surface of a solid carrier, b) analyte or group of analytes is incubated with a detection probe, c) then the solid carrier is washed to remove unbound detection probe, and subsequently, the amount of bound detection probe is determined.
Permanent Link: http://hdl.handle.net/11104/0312846