Degradation of mechanical properties of magnesium alloy

0534523 - ÚSMH 2021 RIV CZ eng C - Conference Paper (international conference)
Sedláček, R. - Suchý, Tomáš - Padovec, Z.
Degradation of mechanical properties of magnesium alloy.
Experimental Stress Analysis (EAN 2019). Praha: Česká společnost pro mechaniku, 2019 - (Petruška, J.; Návrat, T.; Houfek, L.; Šebek, F.), s. 459-461. ISBN 978-802145766-9.
[International Scientific Conference on Experimental Stress Analysis /57./ EAN 2019. Luhačovice (CZ), 03.06.2019-06.06.2019]
Institutional support: RVO:67985891
Keywords : Bioabsorbable metals * Biodegradation * Magnesium * Implant
OECD category: Applied mechanics
https://www.researchgate.net/publication/333679700_Degradation_of_mechanical_properties_of_magnesium_alloy

In this study, biodegradation behaviour of WE43 magnesium alloy have been studied and compared during exposure to three different media commonly used to simulate the conditions of human body environment. Magnesium alloys emerged as a new class of bioresorbable implant materials. Their applications reduce certain risks associated with conventional permanent implants. Biodegradation behaviour of the WE43 magnesium alloy was observed under Dulbecco Modified Eagle Medium (DMEM, Sigma Aldrich) supplemented with 5 % fetal bovine serum and gentamicin antibiotic as standard. The samples were stored in the medium at 37 degrees C and in a 5 % CO2 atmosphere. The second type of medium was Hank's Salt Balanced Solution (HBSS, Sigma Aldrich), which simulates the inorganic composition of blood plasma. HBSS was tempered at 37 degrees C. The last solution was an acidic solution of HCl + NaCl (pH2) with pH similar to 2 (0.01M HCl and 0.14M NaCl) tempered at 37 degrees C. The acidic type of solution was used to simulate a local acidic environment associated with osteoclast activity during bone remodelling. Changes in the mechanical properties of the samples during exposure to simulated body conditions were observed.
Permanent Link: http://hdl.handle.net/11104/0313343