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Photodynamic-active smart biocompatible material for an antibacterial surface coating
- 1.0532315 - ÚFCH JH 2021 RIV CH eng J - Journal Article
Kováčová, M. - Kleinová, A. - Vajďák, J. - Humpolíček, P. - Kubát, Pavel - Bodík, M. - Marković, Z. - Špitálský, Z.
Photodynamic-active smart biocompatible material for an antibacterial surface coating.
Journal of Photochemistry and Photobiology. B - Biology Section. Roč. 211, OCT 2020 (2020), č. článku 112012. ISSN 1011-1344. E-ISSN 1873-2682
R&D Projects: GA MŠMT EF16_019/0000778
Institutional support: RVO:61388955
Keywords : Antibacterial activity * Hydrophobic carbon quantum dots * Nanocomposite * Photodynamic therapy * Radicals
OECD category: Physical chemistry
Impact factor: 6.252, year: 2020
Method of publishing: Limited access
Here we present a new effective antibacterial material suitable for a coating, e.g., surface treatment of textiles, which is also time and financially undemanding. The most important role is played by hydrophobic carbon quantum dots, as a new type of photosensitizer, produced by carbonization of different carbon precursors, which are incorporated by swelling from solution into various polymer matrices in the form of thin films, in particular polyurethanes, which are currently commercially used for industrial surface treatment of textiles. The role of hydrophobic carbon quantum dots is to work as photosensitizers upon irradiation and produce reactive oxygen species, namely singlet oxygen, which is already known as the most effective radical for elimination different kinds of bacteria on the surface or in close proximity to such modified material. Therefore, we have mainly studied the effect of hydrophobic carbon quantum dots on Staphylococcus aureus and the cytotoxicity tests, which are essential for the safe handling of such material. Also, the production of singlet oxygen by several methods (electron paramagnetic spectroscopy, time-resolved near-infrared spectroscopy), surface structures (atomic force microscopy and contact angle measurement), and the effect of radiation on polymer matrices were studied. The prepared material is easily modulated by end-user requirements.
Permanent Link: http://hdl.handle.net/11104/0310835
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