Number of the records: 1
Reductive Alkylation of Amines with Carboxylic Ortho Esters
- 1.0525489 - ÚACH 2021 RIV DE eng J - Journal Article
Kadyrov, Renat - Moebus, K.
Reductive Alkylation of Amines with Carboxylic Ortho Esters.
Advanced Synthesis & Catalysis. Roč. 362, č. 16 (2020), s. 3352-3357. ISSN 1615-4150. E-ISSN 1615-4169
Institutional support: RVO:61388980
Keywords : Alkylation * Amines * Heterogeneous catalysis * Hydrogenation * Ortho esters
OECD category: Inorganic and nuclear chemistry
Impact factor: 5.837, year: 2020
Method of publishing: Open access with time embargo
We have demonstrated for the first time that carboxylic ortho esters could be used as an alkylating agent in the reductive alkylation of amines. A variety of amines, including amino acid esters, were alkylated affording mono-alkylated products with high selectivity in practical to high yields using standard heterogeneous catalysts. By applying acyclic ortho esters alkylation was completed at room temperature. (Figure presented.).
Permanent Link: http://hdl.handle.net/11104/0310678
File Download Size Commentary Version Access Reductive.pdf 1 2.7 MB Author’s postprint open-access SI.pdf 1 2.3 MB Author’s postprint open-access
Number of the records: 1