Biophysical simulation tool PARTRAC: Modelling proton beams at therapy-relevant energies

0523897 - ÚJF 2021 RIV US eng J - Journal Article
Friedland, W. - Kundrát, Pavel - Becker, J. - Eidemuller, M.
Biophysical simulation tool PARTRAC: Modelling proton beams at therapy-relevant energies.
Radiation Protection Dosimetry. Roč. 186, 2-3 (2019), s. 172-175. ISSN 0144-8420. E-ISSN 1742-3406
Institutional support: RVO:61389005
Keywords : Deoxyribonucleic acid * traks * secondary electrons
OECD category: Radiology, nuclear medicine and medical imaging
Impact factor: 0.773, year: 2019
Method of publishing: Limited access
https://doi.org/10.1093/rpd/ncz197

The biophysical simulation tool PARTRAC has been primarily developed to model radiation physics, chemistry and biology on nanometre to micrometre scales. However, the tool can be applied in simulating radiation effects in an event-by-event manner over macroscopic volumes as well. Benchmark simulations are reported showing that PARTRAC does reproduce the macroscopic Bragg peaks of proton beams, although the penetration depths are underestimated by a few per cent for high-energy beams. PARTRAC also quantifies the increase in DNA damage and its complexity along the beam penetration depth. Enhanced biological effectiveness is predicted in particular within distal Bragg peak parts of therapeutic proton beams.
Permanent Link: http://hdl.handle.net/11104/0308178