Iron oxide nanozyme as catalyst of nanogelation

0523537 - ÚMCH 2021 RIV NL eng J - Journal Article
Šálek, Petr - Golunova, Anna - Dvořáková, Jana - Pavlova, Ewa - Macková, Hana - Proks, Vladimír
Iron oxide nanozyme as catalyst of nanogelation.
Materials Letters. Roč. 269, 15 June (2020), s. 1-4, č. článku 127610. ISSN 0167-577X. E-ISSN 1873-4979
R&D Projects: GA ČR(CZ) GA18-03224S; GA MŠMT(CZ) LQ1604
Institutional support: RVO:61389013
Keywords : catalyst * crosslinking * iron oxide nanoparticles
OECD category: Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
Impact factor: 3.423, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0167577X20303153?via%3Dihub

Iron oxide nanoparticles (IONPs) with intrinsic peroxidase-like activity were proven to be effective and direct catalyst of the nanogelation of synthetic polypeptide precursor poly[N5-(2-hydroxypropyl)-L-glutamine-ran-N5-propragyl-L-glutamine-ran-N5-(6-aminohexyl)-L-glutamine]-ran-N5-[2-(4-hydroxyphenyl)ethyl)-L-glutamine] (P2HPG). IONPs catalytic activity and kinetics were determined to mimic the horseradish peroxidase (HRP) used in the nanogelation of the polymer precursor containing a phenol moiety. The prepared nanogels were characterized by dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), and (cryogenic) transmission electron microscopy (cryo-TEM/TEM). Smart IONPs-catalyzed nanogelation resulted in soft and spherical nanoparticles with diameter of approximately 80 nm.
Permanent Link: http://hdl.handle.net/11104/0308166