Nucleotide transport and metabolism in diatoms

0519663 - BC 2020 RIV CH eng J - Journal Article
Gruber, Ansgar - Haferkamp, I.
Nucleotide transport and metabolism in diatoms.
Biomolecules. Roč. 9, č. 12 (2019), č. článku 761. E-ISSN 2218-273X
R&D Projects: GA MŠMT(CZ) EF16_019/0000759
Institutional support: RVO:60077344
Keywords : Adenosine triphosphate (ATP) * Endosymbiosis * Evolution * Photosynthesis * Plastid * Synthetic biology * Transport
OECD category: Microbiology
Impact factor: 4.082, year: 2019
Method of publishing: Open access
https://www.mdpi.com/2218-273X/9/12/761

Plastids, organelles that evolved from cyanobacteria via endosymbiosis in eukaryotes, provide carbohydrates for the formation of biomass and for mitochondrial energy production to the cell. They generate their own energy in the form of the nucleotide adenosine triphosphate (ATP). However, plastids of non-photosynthetic tissues, or during the dark, depend on external supply of ATP. A dedicated antiporter that exchanges ATP against adenosine diphosphate (ADP) plus inorganic phosphate (Pi) takes over this function in most photosynthetic eukaryotes. Additional forms of such nucleotide transporters (NTTs), with deviating activities, are found in intracellular bacteria, and, surprisingly, also in diatoms, a group of algae that acquired their plastids from other eukaryotes via one (or even several) additional endosymbioses compared to algae with primary plastids and higher plants. In this review, we summarize what is known about the nucleotide synthesis and transport pathways in diatom cells, and discuss the evolutionary implications of the presence of the additional NTTs in diatoms, as well as their applications in biotechnology.
Permanent Link: http://hdl.handle.net/11104/0304660