Mn-Zn ferrite nanoparticles coated with mesoporous silica as core material for heat-triggered release of therapeutic agents

0519363 - FZÚ 2020 RIV NL eng J - Journal Article
Stergar, J. - Jirák, Zdeněk - Veverka, Pavel - Kubíčková, Lenka - Vrba, T. - Kuličková, Jarmila - Knížek, Karel - Porcher, F. - Kohout, J. - Kaman, Ondřej
Mn-Zn ferrite nanoparticles coated with mesoporous silica as core material for heat-triggered release of therapeutic agents.
Journal of Magnetism and Magnetic Materials. Roč. 475, Apr (2019), s. 429-435. ISSN 0304-8853. E-ISSN 1873-4766
R&D Projects: GA ČR GA16-04340S
Institutional support: RVO:68378271
Keywords : magnetic nanoparticles * hydrothermal synthesis * Mössbauer spectroscopy * neutron diffraction * Porosimetry
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 2.717, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.jmmm.2018.11.020

Hydrothermal synthesis was employed to prepare three samples of Mn-Zn ferrite nanoparticles with the mean size of crystallites of 12–14 nm, whose compositions were accurately determined by X-ray fluorescence spectroscopy to Mn0.82Zn0.21Fe1.97O, Mn0.70Zn0.31Fe1.99O4, and Mn0.62Zn0.41Fe1.97O4. The X-ray diffraction and SQUID magnetometry were used to determine the spinel structure and ferrimagnetic properties of the samples. AC field heating experiments were performed on particles dispersed in glycerol to evaluate the specific absorption rate. Cation distribution was determined in 10-nm sized Mn0.6Zn0.4Fe2O4 particles. Small clusters of Mn-Zn ferrite crystallites were coated with mesoporous silica. The mesoporous shell was loaded with rhodamine B as a hydrophilic model compound. The shell was sealed by a temperature-sensitive gatekeeper to control the release.
Permanent Link: http://hdl.handle.net/11104/0304357