A heterodinuclear complex of s-d block containing sodium(I), manganese(II) and the enrofloxacinate anion: Preparation, crystal structure and antibacterial activity

0518982 - FZÚ 2020 RIV NL eng J - Journal Article
Hakimi, M. - Alikhani, M. - Mashreghi, M. - Feizi, N. - Raeisi, E. - Mirzai, Y. - Eigner, Václav - Dušek, Michal
A heterodinuclear complex of s-d block containing sodium(I), manganese(II) and the enrofloxacinate anion: Preparation, crystal structure and antibacterial activity.
Journal of Molecular Structure. Roč. 1186, June (2019), s. 355-361. ISSN 0022-2860. E-ISSN 1872-8014
R&D Projects: GA MŠMT(CZ) LO1603
EU Projects: European Commission(CZ) CZ.2.16/3.1.00/24510
Institutional support: RVO:68378271
Keywords : enrofloxacin * manganese(II) * heterodinuclear complex * crystal structure * carboxylate bridge * antimicrobial activity
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 2.463, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.molstruc.2019.03.051

In the present work, the first manganese(II) heterodinuclear complex with enrofloxacin has been synthesized and characterized using the following methods: elemental analysis, FT-IR, Raman, ultraviolet evisible spectroscopy, molar conductivity and single-crystal X-ray diffraction. In the complex structure, the deprotonated bidentate enrofloxacin ligands are coordinated to manganese(II) via the pyridone oxygens and carboxylato oxygens. Sodium(I) is surrounded by carboxylate oxygens from three Enro ligands and oxygens from three water molecules. The antimicrobial activity of the complex was evaluate d against Escherichia coli and Staphylococcus aureus strains by using broth microdilution, well diffusion, and growth inhibition methods. In all experiments, a higher antimicrobial activity of the complex was observed compared to the free ligand.
Permanent Link: http://hdl.handle.net/11104/0303979