PARV4 found in wild chimpanzee faeces: an alternate route of transmission?

0518829 - BC 2020 RIV AT eng J - Journal Article
Brožová, K. - Modrý, David - Dadáková, E. - Mapua, M. I. - Piel, A. K. - Stewart, F. A. - Celer, V. - Hrazdilová, K.
PARV4 found in wild chimpanzee faeces: an alternate route of transmission?
Archives of Virology. Roč. 164, č. 2 (2019), s. 573-578. ISSN 0304-8608. E-ISSN 1432-8798
Institutional support: RVO:60077344
Keywords : human parvovirus 4 * issa valley * infection * prevalence * epidemiology * algorithm * gorillas * children * b19
OECD category: Virology
Impact factor: 2.243, year: 2019
Method of publishing: Open access
https://link.springer.com/article/10.1007%2Fs00705-018-4073-6

Human parvovirus 4 (PARV4, family Parvoviridae, genus Tetraparvovirus) displays puzzling features, such as uncertain clinical importance/significance, unclear routes of transmission, and discontinuous geographical distribution. The origin, or the general reservoir, of human PARV4 infection is unknown. We aimed to detect and characterize PARV4 virus in faecal samples collected from two wild chimpanzee populations and 19 species of captive non-human primates. We aimed to investigate these species as a potential reservoir and alternate route of transmission on the African continent. From almost 500 samples screened, a single wild Pan troglodytes schweinfurthii sample tested positive. Full genome analysis, as well as single ORF phylogenies, confirmed species-specific PARV4 infection.
Permanent Link: http://hdl.handle.net/11104/0304021