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Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of mutation in SACSIN gene
- 1.0517479 - ÚEM 2021 RIV NL eng J - Journal Article
Machuca, C. - Vilches, A. - Clemente, E. - Pascual-Pascual, S.I. - Bolinches-Amorós, A. - Castro, A.A. - Espinos, C. - León, M. - Jendelová, Pavla - Erceg, Slaven
Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of mutation in SACSIN gene.
Stem Cell Research. Roč. 33, dec. (2018), s. 166-170. ISSN 1873-5061. E-ISSN 1876-7753
R&D Projects: GA ČR(CZ) GBP304/12/G069; GA MŠMT(CZ) EF15_003/0000419
Institutional support: RVO:68378041
Keywords : ARSACs patient * induced pluripotent stem cells * reprogramming * non-integrative Sendai virus
OECD category: Human genetics
Impact factor: 3.929, year: 2018
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1873506118302617?via%3Dihub
The human iPSC cell line, CARS-FiPS4F1 (ESi064-A), derived from dermal fibroblast from the apparently healthy carrier of the mutation of the gene SACSIN, was generated by non-integrative reprogramming technology using OCT3/4, SOX2, CMYC and KLF4 reprogramming factors. The pluripotency was assessed by immunocytochemistry and RT-PCR. This iPSC line can be used as control for Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) disease.
Permanent Link: http://hdl.handle.net/11104/0302788
Number of the records: 1