Surface modification of nanoparticles for sustaining sensitivity of surface-enhanced raman spectrometric measurements in salinated environment

0509751 - ÚIACH 2021 RIV CZ eng C - Conference Paper (international conference)
Týčová, Anna - Přikryl, Jan - Vaňhara, P. - Klepárník, Karel - Foret, František
Surface modification of nanoparticles for sustaining sensitivity of surface-enhanced raman spectrometric measurements in salinated environment.
NANOCON Conference Proceedings - International Conference on Nanomaterials. Volume 2020-October. Ostrava: Tanger Ltd., 2020, s. 428-433. 1st Edition. ISBN 978-808729495-6. ISSN 2694-930X.
[NANOCON 2019. International Conference on Nanomaterials - Research & Application /11./. Brno (CZ), 16.10.2019-18.10.2019]
R&D Projects: GA ČR(CZ) GA17-01995S
Institutional support: RVO:68081715
Keywords : bi-ligand * nanoparticle * saline solution * surface-enhanced Raman spectrometry
OECD category: Analytical chemistry
https://www.confer.cz/nanocon/2019

Surface-enhanced Raman spectrometry (SERS) represents a powerful method for analysis of a broad spectrum of analytes ranging from inorganic ions to biomolecules of high complexity. It combines the potential
of Raman spectrometry for a definite identification of an analyte with remarkable sensitivity achieved by the surface enhancement effect occurring on metal nanoparticles. While low ionic strength influences positively
the sensitivity of the SERS measurement, a higher level of inorganic salts leads to fast ruining of colloidal character, which completely devastates the effect of the surface enhancement. The common stabilization of
nanoparticles by a layer of polymers has a negative impact on the SERS sensitivity since it shields the nanoparticle surface from the analytes. In this work, we aim at the development of the bi-ligand system of
nanoparticles surface modification for improved stability of colloid in saline solution at sustaining the potential for sensitive SERS analyses. The proposed system relies on the binding of 3-mercaptopropionic acid and
thiolated polyethylene glycol in a suitable ratio onto the nanoparticle surfaces. While the short chains of the acid sustain the accessibility of the surface for analytes, the polymeric structures act as a steric barrier
preventing colloid aggregation.
Permanent Link: http://hdl.handle.net/11104/0300383