The relationship between ECG predictors of cardiac resynchronization therapy benefit

0508397 - ÚPT 2020 RIV US eng J - Journal Article
Halámek, Josef - Leinveber, P. - Viščor, Ivo - Smíšek, Radovan - Plešinger, Filip - Vondra, Vlastimil - Lipoldová, J. - Matějková, M. - Jurák, Pavel
The relationship between ECG predictors of cardiac resynchronization therapy benefit.
PLoS ONE. Roč. 14, č. 5 (2019), č. článku e0217097. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GA17-13830S; GA MŠMT(CZ) LO1212
Institutional support: RVO:68081731
Keywords : bundle-branch block * QRS duration * CRT
OECD category: Cardiac and Cardiovascular systems
Impact factor: 2.740, year: 2019
Method of publishing: Open access
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0217097&type=printable

Cardiac resynchronization therapy (CRT) is an effective treatment that reduces mortality and improves cardiac function in patients with left bundle branch block (LBBB). However, about 30% of patients passing the current criteria do not benefit or benefit only a little from CRT. Three predictors of benefit based on different ECG properties were compared: 1) ´strict´ left bundle branch block classification (SLBBB), 2) QRS area, 3) ventricular electrical delay (VED) which defines the septal-lateral conduction delay. These predictors have never been analyzed concurrently. We analyzed the relationship between them on a subset of 602 records from the MADIT-CRT trial.

Permanent Link: http://hdl.handle.net/11104/0299315