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Na+/K+-ATPase and lipid peroxidation products in the forebrain cortex of sleep-deprived rats treated with therapeutic lithium
- 1.0507786 - ÚIACH 2020 US eng A - Abstract
Vošahlíková, Miroslava - Roubalová, Lenka - Hloušková, Martina - Cechová, Kristína - Musil, Stanislav - Mikšík, Ivan - Alda, M. - Svoboda, Petr
Na+/K+-ATPase and lipid peroxidation products in the forebrain cortex of sleep-deprived rats treated with therapeutic lithium.
Journal of Neurochemistry. Wiley. Roč. 150, Suppl. 1 (2019), s. 222-223. ISSN 0022-3042. E-ISSN 1471-4159.
[ISN-ASN 2019 Meeting. 04.08.2019-08.08.2019, Montreal]
Institutional support: RVO:68081715 ; RVO:67985823
Keywords : lithium * sleep deprivation * Na+/K+-ATPase
OECD category: Analytical chemistry
Lithium is a typical mood stabilizer representing the first choice for treatment of bipolar disorder. Its mechanisms of action was investigated using sleep deprivation as an animal model of mania and the 1, 7 and 28 days effects of the therapeutic Li concentration on Na+/K+-ATPase properties and lipid peroxidation products amount in the forebrain cortex of rats were compared.
Permanent Link: http://hdl.handle.net/11104/0298758
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Number of the records: 1