Dimethinium Heteroaromatic Salts as Building Blocks for Dual-Fluorescence Intracellular Probes

0507054 - ÚMG 2020 RIV DE eng J - Journal Article
Bříza, T. - Králová, Jarmila - Rimpelová, S. - Havlík, M. - Kaplánek, R. - Kejik, Z. - Reddy, B. - Záruba, K. - Ruml, T. - Mikula, I. - Martásek, P. - Král, V.
Dimethinium Heteroaromatic Salts as Building Blocks for Dual-Fluorescence Intracellular Probes.
ChemPhotoChem. Roč. 1, č. 10 (2017), s. 442-450. ISSN 2367-0932. E-ISSN 2367-0932
R&D Projects: GA MŠMT LO1220; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : living cells * emission * derivatives * sensor * dye * viscosity * protein * design * cell imaging * dual emission * eukaryotic cell lines * fluorescence microscopy * fluorescent probes
OECD category: Cell biology
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cptc.201700061

A series of fluorescent probes based on 2--anilidovinyl-N-alkyl-heteroaromatic salts was prepared. The selective intracellular localization of these probes in mitochondria and lysosomes was demonstrated. Remarkably, some of the probes exhibit unusual dichromic behavior, whereby, in just one step, the salts can be visualized in mitochondria and lysosomes at fluorescence emission wavelengths distinct from each other (dual emitters).
Permanent Link: http://hdl.handle.net/11104/0298148