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Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode
- 1.0506554 - BFÚ 2020 RIV CZ eng C - Conference Paper (international conference)
Hejduková, M. - Špaček, Jan - Fojta, Miroslav - Havran, L. - Renciuk, D.
Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode.
XXXVIII. Moderní elektrochemické metody. Sborník přednášek. Ústí nad Labem: Best Servis, 2018 - (Navrátil, T.; Fojta, M.; Schwarzová, K.), Č. 2018 (2018), s. 74-76. ISBN 978-80-905221-6-9.
[Moderní elektrochemické metody /38./. Jetřichovice (CZ), 21.05.2018-25.05.2018]
R&D Projects: GA ČR(CZ) GA16-01625S; GA MŠMT EF15_003/0000477
Institutional support: RVO:68081707
Keywords : Oligonucleotides * Pyrolytic graphite electrode * Linear sweep voltammetry
OECD category: Physical chemistry
Electrochemical oxidation of specifically designed DNA hexamers containing guanine has been studied in aqueous acetate buffet (pH 5) at a pyrolytic graphite electrode (PGE) by linear sweep voltammetry (LSV) Influence of the oligonucleotide composition and concentration was investigated It seems that short oligonucleotides containing guanine produce oxidation signals. which are sensitive to their structural properties Simple electrochemical techniques us may be useful tool for monitoring of structural changes of DNA.
Permanent Link: http://hdl.handle.net/11104/0297787
Number of the records: 1