Computer assisted development of a pneumatic electrospray nebulizer

0506279 - ÚIACH 2020 RIV CZ eng C - Conference Paper (international conference)
Járvás, G. - Szigeti, M. - Grym, Jakub - Foret, František - Guttman, A.
Computer assisted development of a pneumatic electrospray nebulizer.
CECE 2014. 11th International Interdisciplinary Meeting on Bioanalysis. Brno: Institute of Analytical Chemistry AS CR, 2014 - (Foret, F.; Křenková, J.; Drobníková, I.; Guttman, A.; Klepárník, K.), s. 266-269. ISBN 978-80-904959-2-0.
[CECE 2014. International Interdisciplinary Meeting on Bioanalysis /11./. Brno (CZ), 20.10.2014-22.10.2014]
Institutional support: RVO:68081715
Keywords : microfabricated ESI-MS * electrospray mass spectrometry * pneumatic electrospray nebulizer
OECD category: Analytical chemistry
http://www.ce-ce.org/user_uploads/history/CECE2014_Brno/CECE_2014_proceedings_full.pdf

In this study we demonstrate how computer simulations can assist the development of a novel microfabricated pneumatic electrospray nebulizer. The microdevice under consideration is designed for electrospray mass spectrometry interfacing without the need to fabricate an electrospray needle. This new interfacing strategy requires comprehensive evaluation of the differently designed chip layouts. The flow evaluation was supported by computational fluid dynamics simulations. It was proved with experimental validation of the simulation results that the developed models were practical tools for the numerical investigation of the separations-ESI-MS coupling.
Permanent Link: http://hdl.handle.net/11104/0297954