Polymorphism and thermophysical properties of L- and DL-menthol

0505252 - FZÚ 2020 RIV GB eng J - Journal Article
Štejfa, V. - Bazyleva, A. - Fulem, M. - Rohlíček, Jan - Skořepová, E. - Růžička, K. - Blokhin, A.V.
Polymorphism and thermophysical properties of L- and DL-menthol.
Journal of Chemical Thermodynamics. Roč. 131, Apr (2019), s. 524-543. ISSN 0021-9614. E-ISSN 1096-3626
R&D Projects: GA MŠMT(CZ) LO1603
EU Projects: European Commission(CZ) CZ.2.16/3.1.00/24510
Institutional support: RVO:68378271
Keywords : monoterpenoids * menthol * vapour pressure * heat capacity * variable-temperature XRPD * thermodynamic properties * ideal gas * statistical thermodynamics
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Impact factor: 2.888, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.jct.2018.11.004

The thermodynamic properties, phase behaviour, and kinetics of polymorphic transformations of racemic (dl-) and enantiopure (l-) menthol were studied using a combination of advanced experimental techniques, including static vapour pressure measurements, adiabatic calorimetry, Tian-Calvet calorimetry, differential scanning calorimetry (DSC), and variable-temperature X-ray powder diffraction. Several concomitant polymorphs (α, β, γ, and δ forms) were observed and studied. A continuous transformation to the stable α form was detected by DSC and monitored in detail using X-ray powder diffraction . A long-term coexistence of the stable crystalline form with the liquid phase was observed.
Permanent Link: http://hdl.handle.net/11104/0296736