Number of the records: 1
Detection of Distinct Changes in Gene-expression Profiles in Specimens of Tumors and Transition Zones of Tenascin-positive/-negative Head and Neck Squamous Cell Carcinoma
- 1.0502489 - ÚMG 2019 RIV GR eng J - Journal Article
Živicová, V. - Gal, P. - Mifkova, A. - Novák, S. - Kaltner, H. - Kolář, Michal - Strnad, Hynek - Šáchová, Jana - Hradilová, Miluše - Chovanec, M. - Gabius, H. J. - Smetana, K. - Fík, Z.
Detection of Distinct Changes in Gene-expression Profiles in Specimens of Tumors and Transition Zones of Tenascin-positive/-negative Head and Neck Squamous Cell Carcinoma.
Anticancer Research. Roč. 38, č. 3 (2018), s. 1279-1290. ISSN 0250-7005. E-ISSN 1791-7530
R&D Projects: GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : Extracellular matrix * fibronectin * galectin * tenascin * tumor * stroma
OECD category: Biochemistry and molecular biology
Impact factor: 1.935, year: 2018
Background/Aim: Having previously initiated genome-wide expression profiling in head and neck squamous cell carcinoma (HNSCC) for regions of the tumor, the margin of surgical resecate (MSR) and normal mucosa (NM), we here proceed with respective analysis of cases after stratification according to the expression status of tenascin (Ten). Materials and Methods: Tissue specimens of each anatomical site were analyzed by immunofluorescent detection of Ten, fibronectin (Fn) and galectin-1 (Gal-1) as well as by microarrays.
Permanent Link: http://hdl.handle.net/11104/0294418
Number of the records: 1