Analysis of Cutaneous Microbiota of Piglets with Hereditary Melanoma

0500806 - ÚŽFG 2019 RIV CZ eng J - Journal Article
Švejstil, R. - Salmonová, H. - Čížková, Jana
Analysis of Cutaneous Microbiota of Piglets with Hereditary Melanoma.
Scientia Agriculturae Bohemica. Roč. 49, č. 4 (2018), s. 285-290. ISSN 1211-3174. E-ISSN 1805-9430
R&D Projects: GA MŠMT(CZ) LO1609
Institutional support: RVO:67985904
Keywords : bacteria * skin * cancer
OECD category: Microbiology

Malignant melanoma may be a life-threatening disease caused by various conditions. Cutaneous bacteria could play a role in melanoma development or regression. The present work aimed to analyze the bacterial species present on the epidermis of piglets with hereditary melanoma. Bacteria isolated by swabs directly from melanomas and healthy epidermis were analysed using MALDI-TOF mass spectrometry. From the total of 290 isolates, 92 were identified, while the extraction by ethanol turned out to be more efficient compared to identification by direct transfer. Staphylococcus sciuri, Staphylococcus cohnii, and Lactococcus lactis were significantly more frequent on healthy skin, whereas Staphylococcus chromogenes, Staphylococcus hyicus, and Enterococcus faecalis have thrived significantly better on melanoma. Overall, the results indicate that the micro-biota of melanoma is different from that of healthy epidermis, so piglet skin bacteria inspections are recommended.
Permanent Link: http://hdl.handle.net/11104/0292841