Ultra-performance supercritical fluid chromatography: a powerful tool for the enantioseparation of thermotropic fluorinated liquid crystals

0500366 - FZÚ 2019 RIV NL eng J - Journal Article
Vaňkátová, Petra - Kalíková, K. - Kubíčková, A.
Ultra-performance supercritical fluid chromatography: a powerful tool for the enantioseparation of thermotropic fluorinated liquid crystals.
Analytica Chimica Acta. Roč. 1038, Dec (2018), s. 191-197. ISSN 0003-2670. E-ISSN 1873-4324
Institutional support: RVO:68378271
Keywords : supercritical fluid chromatography * enantioseparation * liquid crystalline materials * chiral fluorinated liquid crystals * amylose
OECD category: Analytical chemistry
Impact factor: 5.256, year: 2018

A supercritical fluid chromatography method for the enantioseparation of orthoconic antiferroelectric liquid crystals is reported. The effects of alkoxy spacer length and fluorine presence and position on the phenyl ring on chromatographic behaviour were investigated. Baseline enantioseparation of all compounds was achieved using simple mobile phases consisting of carbon dioxide and alcohol with amylose tris(3,5-dimethylphenylcarbamate) as chiral stationary phase. The analysis times ranged from 2 to 4 and from 4 to 7 min for most samples with methanol and propane-2-ol, respectively. The effect of cosolvent type on the enantioseparation was assessed and partial complementarity of methanol and propane-2-ol was observed.
Permanent Link: http://hdl.handle.net/11104/0292449