Influence of photoinduced isomerization on the chiral separation of novel liquid crystalline materials with a diazene moiety

0500364 - FZÚ 2019 RIV DE eng J - Journal Article
Jurkovičová, Terézia - Cigl, Martin - Tomášková, Petra - Hamplová, Věra - Sýkora, D.
Influence of photoinduced isomerization on the chiral separation of novel liquid crystalline materials with a diazene moiety.
Journal of Separation Science. Roč. 41, č. 15 (2018), s. 3034-3041. ISSN 1615-9306. E-ISSN 1615-9314
R&D Projects: GA ČR GA16-12150S
Institutional support: RVO:68378271
Keywords : chiral separation * diazenes * high-performance liquid chromatography * liquid-crystalline materials * photoinduced isomerization
OECD category: Analytical chemistry
Impact factor: 2.516, year: 2018

The influence of photoinduced isomerization on the enantiomeric separation of two newly synthesized liquid crystalline materials (with one chiral center and one diazene moiety) was studied by high-performance liquid chromatography on a chiral stationary phase. There were separated into their E and Z isomeric forms. Under the optimized conditions, we were able to separate the S and R enantiomers of both materials in their E isomeric form. The chiral separation of LC 1 possessing a similar structure to LC 2 provided baseline separation in its Z isomeric form, but separation of LC 2 after UV irradiation was unsuccessful. We demonstrate that (1) much more complex compounds can also be successfully separated despite the bulkiness of the achiral part of the structure and (2) photoinduced isomerization even for such complex molecules still strongly influences their chromatographic properties.
Permanent Link: http://hdl.handle.net/11104/0292448