Electromagnetic fields and optomechanics in cancer diagnostics and treatment

0499918 - ÚFE 2019 RIV US eng J - Journal Article
Salari, V. - Barzanjeh, Sh. - Cifra, Michal - Simon, C. - Scholkmann, F. - Alirezaei, Z. - Tuszyński, J.A.
Electromagnetic fields and optomechanics in cancer diagnostics and treatment.
Frontiers in Bioscience. Roč. 23, č. 8 (2018), s. 1391-1406. ISSN 1093-9946. E-ISSN 1093-4715
R&D Projects: GA ČR(CZ) GA15-17102S; GA ČR(CZ) GA17-11898S
Grant - others:AV ČR(CZ) SAV-15-22
Program: Bilaterální spolupráce
Institutional support: RVO:67985882
Keywords : Electromagnetic fields * Cancer * Microtubule
OECD category: Electrical and electronic engineering
Impact factor: 2.214, year: 2018

In this paper, we discuss biological effects of electromagnetic (EM) fields in the context of cancer biology. In particular, we review the nanomechanical properties of microtubules (MTs), the latter being one of the most successful targets for cancer therapy. We propose an investigation on the coupling of electromagnetic radiation to mechanical vibrations of MTs as an important basis for biological and medical applications. In our opinion, optomechanical methods can accurately monitor and control the mechanical properties of isolated MTs in a liquid environment. Consequently, studying nanomechanical properties of MTs may give useful information for future applications to diagnostic and therapeutic technologies involving non-invasive externally applied physical fields. For example, electromagnetic fields or high intensity ultrasound can be used therapeutically avoiding harmful side effects of chemotherapeutic agents or classical radiation therapy
Permanent Link: http://hdl.handle.net/11104/0292105