Amphiphilic compounds with neuroprotective properties

0499626 - ÚOCHB 2019 RIV eng P - Patent Document
Kudová, Eva - Chodounská, Hana - Kapras, Vojtěch - Vyklický ml., Ladislav - Valeš, Karel - Jahn, Ullrich
Amphiphilic compounds with neuroprotective properties.
2018. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. Date of the patent acceptance: 10.07.2018. Patent Number: US10017535
R&D Projects: GA TA ČR(CZ) TE01020028; GA ČR(CZ) GBP304/12/G069
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : steroid * NMDA receptor * neuroprotective
OECD category: Organic chemistry; Pharmacology and pharmacy (FGU-C)
https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=US&NR=10017535B2&KC=B2&FT=D&ND=4&date=20180710&DB=&locale=en_EP#

Amphiphilic compounds with tetradecahydrophenanthrene skeleton and their enantiomers, exhibiting neuroprotective effects, their use in methods of treatment of neuropsychiatric disorders associated with an imbalance in glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post-traumatic stress disorder and diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addiction, multiple sclerosis, epilepsy, glioma, and a pharmaceutical composition containing compound.
Permanent Link: http://hdl.handle.net/11104/0291870