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Design and synthesis of novel thiourea metal complexes with controllable antibacterial properties

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    0498661 - FZÚ 2019 RIV GB eng J - Journal Article
    Rakhshani, S. - Rezvani, A.R. - Dušek, Michal - Eigner, Václav
    Design and synthesis of novel thiourea metal complexes with controllable antibacterial properties.
    Applied Organometallic Chemistry. Roč. 32, č. 6 (2018), s. 1-13, č. článku 4342. ISSN 0268-2605. E-ISSN 1099-0739
    R&D Projects: GA ČR GA15-12719S; GA MŠMT(CZ) LO1603
    EU Projects: European Commission(CZ) CZ.2.16/3.1.00/24510
    Institutional support: RVO:68378271
    Keywords : bacteria inactivation * colony count method * DFT * hydrogen bond * oxazolidine derivative
    OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
    Impact factor: 3.259, year: 2018

    A new bidentate O,S donor thiourea ligand (L1), namely N‐(2‐hydroxyethyl)‐N′‐2‐chlorobenzoylthiourea, and its oxazolidine derivative (L2) were synthesized. Derivative L2 was used for the preparation of Ni(L2)2 and Cu(L2)2 complexes. The compounds were investigated using X‐ray crystallography and Fourier transform infrared, 1H NMR and UV–visible spectroscopies. In addition, the antibacterial activities of these compounds were evaluated against Gram‐positive and Gram‐negative bacteria, measured using the colony count method.
    Permanent Link: http://hdl.handle.net/11104/0291815

     
     
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