Micro-CT in tissue engineering scaffolds designed for bone regeneration: Principles and applications

0497409 - ÚSMH 2019 RIV CZ eng J - Journal Article
Bartoš, M. - Suchý, Tomáš - Tonar, Z. - Foltán, R. - Hubálek Kalbáčová, M.
Micro-CT in tissue engineering scaffolds designed for bone regeneration: Principles and applications.
Ceramics - Silikáty. Roč. 62, č. 2 (2018), s. 194-199. ISSN 0862-5468. E-ISSN 1804-5847
R&D Projects: GA MZd(CZ) NV15-25813A
Institutional support: RVO:67985891
Keywords : micro-CT * tissue engineering scaffolds * bone regeneration * biomaterials * 3D analysis
OECD category: Anatomy and morphology (plant science to be 1.6)
Impact factor: 0.840, year: 2018
http://www.ceramics-silikaty.cz/index.php?page=cs_detail_doi&id=1211

Micro-CT (micro-computed tomography) is a modern preclinical imaging method allowing non-destructive visualizations and structure analysis yielding at a resolution of a few micrometres. Tissue engineering scaffolds are a promising treatment for bone defects. Micro-CT application for the evaluation of tissue engineering scaffolds for bone surgery and traumatology application is increasing, which comprises in vitro, in vivo and ex vivo studies. Micro-CT itself is not able to replace conventional approaches completely, such as scanning electron microscopy (SEM) or histological examination, but it may offer important benefits regarding non-destructive approach, direct 3D model structure analysis, and visualization and time efficacy. The overview presented herein focuses on a micro-CT application in the field of tissue engineering scaffolds aimed at bone regeneration.
Permanent Link: http://hdl.handle.net/11104/0289986