Histology and micro-CT study of diamond-coated metal bone implants in rabbit femurs

0496851 - FZÚ 2019 RIV CZ eng C - Conference Paper (international conference)
Potocký, Štěpán - Ižák, Tibor - Dragounová, Kateřina - Kromka, Alexander - Rezek, Bohuslav - Mandys, V. - Bartoš, M. - Bačáková, Lucie - Sedmera, David
Histology and micro-CT study of diamond-coated metal bone implants in rabbit femurs.
Nanocon 2017 : conference proceedings : 9th International Conference on Nanomaterials - Research & Application. Ostrava: Tanger Ltd., 2018, s. 573-577. ISBN 9788087294819.
[NANOCON 2017. International Conference on Nanomaterials - Research & Application /9./. Brno (CZ), 18.10.2017-20.10.2017]
R&D Projects: GA MZd(CZ) NV15-32497A
Institutional support: RVO:68378271 ; RVO:67985823
Keywords : screw implant * diamond coating * osteointegration * histology
OECD category: Biophysics; Biomaterials (as related to medical implants, devices, sensors) (FGU-C)

A conformal coating of a thin diamond layer on three-dimensional metal bone implants was shown directly on stainless steel and TiAl6V4 cortical screw implant using ultrasonic and composite polymer pretreatment method. The best conformation coverage was achieved in the case of the WO3 interlayer for both stainless steel and TiAl6V4 screws. The process of osteointegration of the screw implants into rabbit femurs is evidenced by the formation of a bone edge via desmogenous ossification around the screws in less than six months after implantation. A detailed evaluation of the tissue reaction around the implanted screws shows good biocompatibility of diamond-coated metal bone implants.
Permanent Link: http://hdl.handle.net/11104/0289476