Resistive pulse sensing as particle counting and sizing method in microfluidic systems: Designs and applications review

0496557 - ÚIACH 2020 RIV DE eng J - Journal Article
Václavek, Tomáš - Přikryl, Jan - Foret, František
Resistive pulse sensing as particle counting and sizing method in microfluidic systems: Designs and applications review.
Journal of Separation Science. Roč. 42, č. 1 (2019), s. 445-457. ISSN 1615-9306. E-ISSN 1615-9314
R&D Projects: GA ČR(CZ) GBP206/12/G014; GA ČR(CZ) GJ16-09283Y; GA ČR(CZ) GJ18-03367Y
Institutional support: RVO:68081715
Keywords : bioanalysis * electrical impedance spectroscopy * microfluidics * single cell analysis
OECD category: Analytical chemistry
Impact factor: 2.878, year: 2019
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/full/10.1002/jssc.201800978

The resistive pulse sensing is well-known and established method for counting and sizing of particles in ionic solutions. Throughout its development the technique has been expanded from detection of biological cells to counting nanoparticles and viruses, and even registering individual molecules, e.g., nucleotides in nucleic acids. This technique combined with microfluidic or nanofluidic systems shows great potential for various bioanalytical
applications, which were hardly possible in before microfabrication has gained the present broad adoption. In this review, we provide a comprehensive overview of microfluidic designs analysis of single cells that were reported within the past 5 years.
Permanent Link: http://hdl.handle.net/11104/0289298