Number of the records: 1
Silica-based nanoparticles are efficient delivery systems for temoporfin
- 1.0495928 - ÚMG 2019 RIV NL eng J - Journal Article
Brezaniova, I. - Záruba, K. - Králová, Jarmila - Sinica, A. - Adámková, H. - Ulbrich, P. - Pouckova, P. - Hrubý, Martin - Štěpánek, Petr - Král, V.
Silica-based nanoparticles are efficient delivery systems for temoporfin.
Photodiagnosis and Photodynamic Therapy. Roč. 21, Marz (2018), s. 275-284. ISSN 1572-1000. E-ISSN 1873-1597
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LM2015064; GA ČR(CZ) GA17-02448S; GA ČR(CZ) GA16-03156S; GA MZd(CZ) NV16-30544A; GA MŠMT(CZ) LO1304; GA MŠMT(CZ) LQ1604
Institutional support: RVO:68378050 ; RVO:61389013
Keywords : Photodynamic therapy * Drug delivery * Blood-brain barrier * Silica nanoparticles * Temoporfin
OECD category: Cell biology; Polymer science (UMCH-V)
Impact factor: 2.589, year: 2018
Background Drug targeting using functionalized nanoparticles to advance their transport to the dedicated site became a new standard in novel anticancer methods Anticancer photodynamic therapy also takes benefit from using nanoparticles by means of increasing targeting efficiency and decreased side effect. With this in mind, the silica-based nanoparticles, as drug delivery systems for the second-generation photosensitizer 5,10,15,20-tetrakis(m-hydroxyphenyl) chlorin (temoporfin) were developed.
Permanent Link: http://hdl.handle.net/11104/0288801
Number of the records: 1