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Xanthones content in swertia multicaulis D. Don from Nepal
- 1.0490943 - ÚVGZ 2019 RIV CH eng J - Journal Article
Timsina, Binu - Kindlmann, Pavel - Rokaya, Maan Bahadur - Vrchotová, Naděžda - Tříska, Jan - Horník, Štěpán - Sýkora, Jan
Xanthones content in swertia multicaulis D. Don from Nepal.
Molecules. Roč. 23, č. 5 (2018), č. článku 1067. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) LO1415
Institutional support: RVO:86652079 ; RVO:67985858
Keywords : Gentianaceae * hplc * lc–ms * nmr * Phytochemistry * Secondary metabolites * Swertia
OECD category: Biodiversity conservation; Analytical chemistry (UCHP-M)
Impact factor: 3.060, year: 2018
The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S. multicaulis determined by HPLC reaches almost 13 g of xanthones per 1 kg of dry matter. The identification of xanthones in S. multicaulis was achieved by a combination of HPLC, LC–MS and LC–NMR. The final assignment of the individual chemical structures was provided by NMR, supported by preparative HPLC. In eight chromatographic peaks, four major xanthones were identified—1,3-dihydroxy-5,8-dimethoxyxanthone, 1-hydroxy-3,5,8-trimethoxyxanthone, bellidifolin (1,5,8-tri-hydroxy-3-methoxyxanthone), and decussatin (1-hydroxy-3,7,8-trimethoxyxanthone).
Permanent Link: http://hdl.handle.net/11104/0285053
Number of the records: 1