Antibacterial and Antibiofouling Properties of Light Triggered Fluorescent Hydrophobic Carbon Quantum Dots Langmuir-Blodgett Thin Films

0488453 - ÚFCH JH 2019 RIV US eng J - Journal Article
Stanković, N. K. - Bodik, M. - Šiffalovič, P. - Kotlár, M. - Mičušik, M. - Špitalsky, Z. - Danko, M. - Milivojević, D. D. - Kleinová, A. - Kubát, Pavel - Capáková, Z. - Humpolíček, P. - Lehocký, M. - Todorović Marković, B. M. - Marković, Z. M.
Antibacterial and Antibiofouling Properties of Light Triggered Fluorescent Hydrophobic Carbon Quantum Dots Langmuir-Blodgett Thin Films.
ACS Sustainable Chemistry & Engineering. Roč. 6, č. 3 (2018), s. 4154-4163. ISSN 2168-0485. E-ISSN 2168-0485
R&D Projects: GA ČR(CZ) GA17-05095S
Institutional support: RVO:61388955
Keywords : Hydrophobic carbon quantum dots * Langmuir-Blodgett thin films * Photodynamic therapy * Singlet oxygen
OECD category: Physical chemistry
Impact factor: 6.970, year: 2018

Inimitable properties of carbon quantum dots as well as a cheap production contribute to their possible application in biomedicine especially as antibacterial and antibiofouling coatings. Fluorescent hydrophobic carbon quantum dots are synthesized by bottom-up condensation method and used for deposition of uniform and homogeneous Langmuir-Blodgett thin films on different substrates. It is found that this kind of quantum dots generates singlet oxygen under blue light irradiation. Antibacterial and antibiofouling testing on four different bacteria strains (Escherichia coli, Staphylococcus aureus, Bacillus cereus, and Pseudomonas aeruginosa) reveals enhanced antibacterial and antibiofouling activity of hydrophobic carbon dots thin films under blue light irradiation. Moreover, hydrophobic quantum dots show noncytotoxic effect on mouse fibroblast cell line. These properties enable potential usage of hydrophobic carbon quantum dots thin films as excellent antibacterial and antibiofouling coatings for different biomedical applications.
Permanent Link: http://hdl.handle.net/11104/0283038