0486063 - BFÚ 2018 RIV NL eng J - Journal Article
Dvořáková, Zuzana - Vorlíčková, Michaela - Renčiuk, Daniel
Spectroscopic insights into quadruplexes of five-repeat telomere DNA sequences upon G-block damage.
Biochimica et Biophysica Acta-General Subjects. Roč. 1861, č. 11 (2017), s. 2750-2757. ISSN 0304-4165. E-ISSN 1872-8006
R&D Projects: GA ČR(CZ) GJ17-19170Y
Institutional support: RVO:68081707
Keywords : k+ solution * guanine quadruplexes
OECD category: Biochemistry and molecular biology
Impact factor: 3.679, year: 2017

Background: The DNA lesions, resulting from oxidative damage, were shown to destabilize human telomere four repeat quadruplex and to alter its structure. Long telomere DNA, as a repetitive sequence, offers, however, other mechanisms of dealing with the lesion: extrusion of the damaged repeat into loop or shifting the quadruplex position by one repeat.
Permanent Link: http://hdl.handle.net/11104/0280950