- A putative ATP/GTP binding protein affects Leishmania mexicana growth…
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A putative ATP/GTP binding protein affects Leishmania mexicana growth in insect vectors and vertebrate hosts

  1. 1.
    0485197 - BC 2018 RIV US eng J - Článek v odborném periodiku
    Ishemgulova, A. - Kraeva, N. - Hlaváčová, J. - Zimmer, S.L. - Butenko, A. - Podešvová, L. - Leštinová, T. - Lukeš, Julius - Kostygov, A. - Votýpka, Jan - Volf, P. - Yurchenko, V.
    A putative ATP/GTP binding protein affects Leishmania mexicana growth in insect vectors and vertebrate hosts.
    PLoS Neglected Tropical Diseases. Roč. 11, č. 7 (2017), č. článku e0005782. ISSN 1935-2735. E-ISSN 1935-2735
    Grant CEP: GA MŠMT LL1601
    Institucionální podpora: RVO:60077344
    Klíčová slova: multiple sequence alignment * sand flies * trypanosoma-brucei * expression system * p-loop * transmission * evolution * parasites * resource * kinases
    Obor OECD: Biochemistry and molecular biology
    Impakt faktor: 4.367, rok: 2017 ; AIS: 1.476, rok: 2017
    DOI: https://doi.org/10.1371/journal.pntd.0005782

    Leishmania virulence factors responsible for the complicated epidemiology of the various leishmaniases remain mainly unidentified. This study is a characterization of a gene previously identified as upregulated in two of three overlapping datasets containing putative factors important for Leishmania's ability to establish mammalian intracellular infection and to colonize the gut of an insect vector.
    Trvalý link: http://hdl.handle.net/11104/0280366
     
Number of the records: 1  

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