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Structure-activity and mechanistic study of inhibitory effects of polysubstituted pyrimidines on prostaglandin E2 production
- 1.0485195 - ÚOCHB 2018 HR eng A - Abstract
Zídek, Zdeněk - Janeba, Zlatko - Jansa, Petr - Kverka, Miloslav - Kmoníčková, Eva - Kalčic, Filip - Kolman, Viktor
Structure-activity and mechanistic study of inhibitory effects of polysubstituted pyrimidines on prostaglandin E2 production.
10th Joint Meeting on Medicinal Chemistry. Zagreb: Croatian Chemical Society, 2017 - (Basarić, N.; Namjesnik, D.; Perković, I.; Stepanić, V.). s. 241. ISBN 978-953-55232-8-4.
[Joint Meeting on Medicinal Chemistry /10./. 25.06.2017-28.06.2017, Dubrovnik]
R&D Projects: GA TA ČR(CZ) TE01020028
Institutional support: RVO:61388963 ; RVO:68378041
Keywords : pyrimidines * anti-inflammatory * prostaglandin E2
Subject RIV: CC - Organic Chemistry
We have found that polysubstituted pyrimidines are the structure-dependent inhibitors of PGE2 production with anti-inflammatory properties.
Permanent Link: http://hdl.handle.net/11104/0280379
Number of the records: 1