Distribution and deposition of ZNO nanoparticles in mice – Inhalation chamber study

0481445 - ÚIACH 2018 IE eng A - Abstract
Kulich, P. - Šerý, Omar - Večeřa, Zbyněk - Vysloužil, Jan - Mikuška, Pavel - Dočekal, Bohumil - Stráská, J. - Machala, M.
Distribution and deposition of ZNO nanoparticles in mice – Inhalation chamber study.
Toxicology Letters. Elsevier. Roč. 280, SI (2017), S205-S205. ISSN 0378-4274. E-ISSN 1879-3169.
[Congress of the European Societies of Toxicology (EUROTOX) /53./. 10.09.2017-13.09.2017, Bratislava]
R&D Projects: GA ČR(CZ) GBP503/12/G147
Institutional support: RVO:68081715 ; RVO:67985904
Keywords : ZNO nanoparticles * inhalation chamber study * mice
OECD category: Analytical chemistry

Airborne metallic nanoparticles pose a risk to human and animal health. ZnO nanoparticles (ZnONP) are produced by the industrial processing of steel, lead, hot-dip galvanizing, or domestic burning. In our inhalation experiment using a mouse model (in the inhalation chamber), we focused on the toxicity of ZnONP, their penetration into cells and distribution in the lungs, liver, kidneys, spleen and brain.
Permanent Link: http://hdl.handle.net/11104/0277008