The impact of air pollution in the Southern Bohemia Region on fetuses and newborns

0481298 - ÚEM 2018 RIV SE eng J - Journal Article
Veleminský Jr., M. - Hanzl, M. - Šrám, Radim
The impact of air pollution in the Southern Bohemia Region on fetuses and newborns.
Neuroendocrinology Letters. Roč. 37, č. 2 (2016), s. 52-57. ISSN 0172-780X. E-ISSN 2354-4716
R&D Projects: GA ČR(CZ) GA13-13458S
Institutional support: RVO:68378041
Keywords : air pollution * polycyclic aromatic hydrocarbons * benzo[a] pyrene
OECD category: Public and environmental health
Impact factor: 0.918, year: 2016

Air pollution with increased concentrations of carcinogenic polycyclic aromatic hydrocarbons (c-PAHs, represented by benzo[a] pyrene, B[a] P) affects fetal development, reduces birth weights (LBW) of newborns, and increases intrauterine growth retardation (IUGR). The Southern Bohemia Region is believed to be one of the least air polluted regions in the Czech Republic. Monitoring air pollution in the city of Ceske Budejovice from 2011-2015, PM2.5 (particulate matter <2.5 mu m) decreased from 20.3 +/- 14.5 mu g/m(3) to 14.3 +/- 8.6 mu g/m(3), but concentrations of B[a] P did not change between the years 2007-2015: 1.5 +/- 0.6 ng/m(3) vs. 1.4 +/- 0.6 ng/m3. Higher B[a] P concentrations the winter induce genetic damage in newborns, increase frequency of micronuclei (chromosomal aberrations), deregulate genes for immunity in umbilical cord blood, and increase incidence of IUGR and LBW in newborns.
Permanent Link: http://hdl.handle.net/11104/0276882