Number of the records: 1
Lipopolyamines of spermine type for construction of liposomal transfection systems
- 1.0471716 - ÚOCHB 2017 RIV eng P - Patent Document
Drašar, Lukáš - Ledvina, Miroslav - Korvasová, Z. - Turánek, J.
Lipopolyamines of spermine type for construction of liposomal transfection systems.
2016. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Výzkumný ústav veterinárního lékařství, v. v. i. Date of the patent acceptance: 19.07.2016. Patent Number: US9393200
Institutional support: RVO:61388963
Keywords : lipopolyamines * transfection * liposomes
Subject RIV: CC - Organic Chemistry
https://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=9393200B2&KC=B2&FT=D&ND=4&date=20160719&DB=&locale=en_EP#
The invention provides new lipopolyamines of spermine type of the general formula I, wherein X is C—N bond or aminopolyethyleneglycolcarboxamide linker or o-hydroxy-alkylcarboxamide linker or omega-hydroxyalkylcarboxamidopolyethyleneglycol-carboxamide linker, and wherein a hydrophobic domain Y is an acyl symmetrically branched in the position C(2) or cholesteryl. The invention further provides a method of preparation of said lipopolyamines and their use for construction of polycationic liposomal drug carriers.
Permanent Link: http://hdl.handle.net/11104/0269475
Number of the records: 1