Thiol-modified gold-coated glass as an efficient hydrophobic substrate for drop coating deposition Raman (DCDR) technique

0469636 - ÚFE 2017 RIV GB eng J - Journal Article
Kočišová, E. - Procházka, M. - Šípová, Hana
Thiol-modified gold-coated glass as an efficient hydrophobic substrate for drop coating deposition Raman (DCDR) technique.
Journal of Raman Spectroscopy. Roč. 47, č. 11 (2016), s. 1394-1396. ISSN 0377-0486. E-ISSN 1097-4555
R&D Projects: GA ČR(CZ) GBP205/12/G118
Institutional support: RVO:67985882
Keywords : thiol-modified Au-coated glass * drop coating deposition Raman * liposome
Subject RIV: BH - Optics, Masers, Lasers
Impact factor: 2.969, year: 2016

In this paper we report an easy and low-cost way to prepare a hydrophobic substrate for drop coating deposition Raman (DCDR) spectroscopy. This substrate is formed by a thiol-modified Au-coated glass and provides the Raman spectra with the same quality as the commercial Teflon-coated stainless steel substrate (SpectRIM (TM),Tienta Sciences, Inc.) for model molecular systems - albumin solution and liposome suspension. Gold layer, similarly to polished steel in the commercial substrate, served as a highly refractive layer strongly increasing the Raman signal. The main advantage of introduced substrate is that it is simple and a low-cost preparation easily manageable in every standard laboratory. Thus, it represents a promising alternative to commercial Tefloncoated stainless steel substrate
Permanent Link: http://hdl.handle.net/11104/0267458