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Antiviral acyclic nucleoside phosphonates: New structures and prodrugs
- 1.0468507 - ÚOCHB 2017 US eng A - Abstract
Krečmerová, Marcela - Tichý, Tomáš - Pomeisl, Karel - Andrei, G. - Balzarini, J. - Snoeck, R.
Antiviral acyclic nucleoside phosphonates: New structures and prodrugs.
Madridge Journal of Pharmaceutical Research. Roč. 1, č. 2 (2016), s. 37
[PharmaMed-2016. International Conference on Medicinal and Pharmaceutical Chemistry. 05.12.2016-07.12.2016, Dubai]
R&D Projects: GA ČR(CZ) GA14-00522S
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * prodrugs * antivirals * 5-azacytosine
Subject RIV: CC - Organic Chemistry
Synthesis of various antiviral ANP prodrugs is described including newly developed compounds with 5-azacytosine base. Influence of promoiety structures to antiviral activity and pharmacokinetic profile of parent compounds is discussed.
Permanent Link: http://hdl.handle.net/11104/0266341
Number of the records: 1