Comparison of arterial input function models for small-animal ultrasound perfusion imaging

0466798 - ÚPT 2017 RIV US eng C - Conference Paper (international conference)
Mézl, M. - Jiřík, Radovan - Dvořáková, Lenka - Dražanová, Eva - Kolář, R.
Comparison of arterial input function models for small-animal ultrasound perfusion imaging.
IEEE International Ultrasonics Symposium (IUS) 2016. Piscataway: IEEE, 2016, 7728503:1-4. ISBN 978-1-4673-9897-8. E-ISSN 1948-5727.
[IEEE International Ultrasonics Symposium (IUS) 2016. Tours (FR), 18.09.2016-21.09.2016]
R&D Projects: GA MŠMT(CZ) LO1212
Institutional support: RVO:68081731
Keywords : animals * blood * hemodynamics * tissue
Subject RIV: BM - Solid Matter Physics ; Magnetism
http://ieeexplore.ieee.org/abstract/document/7728503/

Quantitative ultrasound perfusion imaging is used to estimate tissue perfusion parameters, such as blood flow, blood volume and mean transit time. The bolus & burst method is one possible approach to quantitative ultrasound perfusion imaging. It is based on a pharmacokinetic model where the tissue intensity curves are modeled as a convolution of an arterial input function (AIF) and an impulse residue function. Two AIF models have been presented for the bolus & burst method so far based on two lognormal and three gamma variate functions. The aim of this contribution is to suggest other alternative AIF models and test their suitability for the bolus & burst method for small-animal applications by comparison with measured AIFs.
Permanent Link: http://hdl.handle.net/11104/0265023